Production Of Transgenic Animals Notes

Animals that have had their DNA manipulated to possess and express a foreign gene are known as transgenic animals.

Production of transgenic animals notes. The foreign gene is constructed using recombinant DNA methodology. The first transgenic animal was produced is mice by injecting DNA to mouse embryos then implanting the embryos in female mice. There are many ways to produce transgenic animals.

Transgenic animals can be created by manipulating embryonic stem cells. The first transgenic animal was produced in 1983 when genes for human growth hormone were introduced into mice. The animals used for transgenic purpose naturally carry the mechanism needed to produce complex protein.

The transgenic animals are created because of the benefits they provide to the man. Let us discuss a few of them here. Transgene is incorporated into the ES cell by Microinjection By a retro virus By electroporation Transgenic stem cells are grown in vitro.

Biotechnology for Sustainable Agriculture 2018. After injecting the DNA the embryo is implanted into the uterus of receptive females. Studying gene function.

Genetically modified animals are proving ever more vital in. Many procedures have been developed to increase the efficiency of this generally inefficient process. One favoured method involves the inoculation of the DNA into the pronucleus of a fertilised ovum followed by implantation into pseudo pregnant females.

Agricultural Applications a Breeding Farmers have always used selective breeding to produce animals that exhibit desired traits eg. Theses mechanism is absent in cell culture. Transgenic animal technologies have come a long way since the creation of the first transgenic mouse in 1974 Transgenic Mouse 2005.